Abstract

IDROVO, Alvaro Javier; SANIN, Luz Helena; DONALD, C  and  COLE, D. Evaluation of time-to-pregnancy as a measure in environmental epidemiology. Biomédica [online]. 2005, vol.25, n.3, pp.398-411. ISSN 0120-4157.

Since the late 80’s, time to pregnancy has been used in environmental epidemiology to explore adverse effects of different exposures. The advantages of this measure and additional elements to be considered in the performance of this type of studies are reviewed. Study design includes the following steps: population selection, sample size, outcome measurement, statistical analyses and sources of bias. Guidelines were suggested for the properly development of this type of study.

Keywords : infertility; epidemiologic methods; epidemiologic research design; survival analysis.

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