SciELO - Scientific Electronic Library Online

vol.29 issue1Persistent type 2 lepra reaction and clofazimine-induced lethal enteropatyEvidence-based medicine: an epistemological approach author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand



Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google



Print version ISSN 0120-4157
On-line version ISSN 2590-7379


MONTOYA, Jorge Hernán  and  MORALES, Olga Lucía. Four cases of Jarcho-Levin’s syndrome in the province of Antioquia, Colombia. Biomédica [online]. 2009, vol.29, n.1, pp.25-32. ISSN 0120-4157.

Jarcho-Levin’s syndrome is a skeletal dysplasia with changes in the morphogenesis and costal vertebrae segmentation. It is manifested by hemivertebrae, fused vertebral bodies, absent vertebrae or fused ribs. This entity has also been called spondylo-costal or spondylo-thoracic dysplasia-dysostosis. This paper presents four cases evaluated at the Hospital University San Vicente de Paúl, Medellín, Colombia. Three had family origins in southwestern Antioquia and one in Medellin, indicating the possibility of a predisposing genetic allele with elevated frequency in this population. The clinical and radiological manifestations were described, a well as the most notable complications, such as restrictive lung disease with permanent oxygen requirement (all 4 patients) and portal hypertension etiology (1 patient).  The latter has not been reported previously as a manifestation of this syndrome.

Keywords : inheritance patterns; gene frequency; congenital abnormalities; spine; ribs; hypertension; portal.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License