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Biomédica

versão impressa ISSN 0120-4157versão On-line ISSN 2590-7379

Resumo

ZARANTE, Ignacio; FRANCO, Liliana; LOPEZ, Catalina  e  FERNANDEZ, Nicolás. Frequencies of congenital malformations: assessment and prognosis of 52,744 births in three cities of Colombia. Biomédica [online]. 2010, vol.30, n.1, pp.65-71. ISSN 0120-4157.

Introduction. The Instituto de Genética Humana of the Pontificia Universidad Javeriana conducted an epidemiological surveillance of congenital malformations as defined by criteria provided by the Latin American Collaborative Study of Congenital Malformations. Objective. The frequency of the main congenital malformations were tabulated for major urban centers in Colombia. Materials and methods. Information was gathered from 52,744 newborns between April 2001 and January 2008 in three cities of Colombia (Bogotá, Ubaté and Manizales). Data included the age of mother, gestational age, gender and weight of the newborn and the congenital malformation. Cases were classified according to a prognostic scale to assess the impact of health team interventions in the recovery process. Results. Congenital defects were noted in 3.1% of the newborns. The most frequent congenital defects were those of the ears. Clubfoot, polydactyly and cleft lip or palate were more common amongst males. The weight and gestational age were lower in the congenitally affected in comparison with the control group. The prognostic scale of congenital malformations indicated that most of these patients are at high risk of death or disability and that the intervention of the health team changed the patient´s prognosis in approximately 80% of the cases. Conclusion. Frequencies of congenital malformations in Colombia were similar to those reported in other countries. The interventions of the health team in treating patients with congenital malformations directly affected patient prognosis. Therefore, early diagnosis and adequate interdisciplinary treatment were recommended by these data in order to reduce disability and improve the quality of life of these patients.

Palavras-chave : congenital abnormalities [epidemiology]; prognosis; infant mortality; disabled children; International Classification of Functioning, Disability and Health.

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