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Biomédica

Print version ISSN 0120-4157

Abstract

RODRIGUEZ-NORIEGA, Eduardo et al. Evolution of bacterial resistance to antibiotics in México, 1973-2013 . Biomédica [online]. 2014, vol.34, suppl.1, pp.181-190. ISSN 0120-4157.  http://dx.doi.org/10.7705/biomedica.v34i0.2142.

Introduction: Bacterial resistance to antibiotics is a worldwide public health concern. Research priorities for the study and control of this emerging problem include country-wide surveillance. Objective: To review and comment on the contributions by Mexican investigators towards a greater understanding of the mechanisms of bacterial antibiotic resistance. Materials and methods: A comprehensive search of the medical literature on Medline/PubMed between 1973 and July 2013 was performed. Results: The contributions of Mexican investigators have included descriptions of resistance in enteric pathogens, such as Salmonella Typhi, publications on the production of extended spectrum beta-lactamases, metallo-beta-lactamases, and carbapenemases, resistance mechanisms of Pseudomonas aeruginosa , and the evolution of resistance in Gram-positive pathogens, including Streptococcus pneumoniae , Staphylococcus aureus , and Enterococcus spp. Conclusion: The Mexican literature on mechanisms of bacterial resistance is relevant for the development of plans to control the antibiotic resistance crisis.

Keywords : Drug resistance, bacterial; Gram-negative bacteria; Gram-positive cocci; beta-lactamases; review literature as topic; Mexico.

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