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Biomédica

versão impressa ISSN 0120-4157

Resumo

MARTINEZ, Julio César; LLERENA, Claudia  e  VALBUENA, Yanely Angélica. Importance of investigating Mycobacterium bovis in clinical samples of human origin. Biomédica [online]. 2019, vol.39, suppl.1, pp.117-124. ISSN 0120-4157.  https://doi.org/10.7705/biomedica.v39i2.4358.

Introduction:

Tuberculosis is an infectious disease that still represents a major public health problem worldwide. It is one of the main causes of mortality in people with HIV.

Objective:

To identify the presence of M. bovis as an etiological agent of human tuberculosis in sputum smear positive samples using the test Genotype MTBC™.

Materials and methods:

We conducted a descriptive study, 88 sputum samples were submitted to the Grupo de Micobacterias of the Instituto Nacional de Salud between January and November, 2015. We used the conventional microbiological analysis and the molecular test Genotype MTBC™ to identify the M. tuberculosis complex species.

Results:

Sixty two (70.5%) were males; the most affected groups were those between 24 and 34 years old, those residing in the municipal seats and those affiliated to the subsidized health plans. In 50.0% (44) of the samples with a result in the species identification test, we detected M. tuberculosis.

Conclusion:

The highest burden of the disease was recorded among the male population in productive ages. The identification test for species of the complex showed all were M. tuberculosis. However, it is not possible to discard the presence of M. bovis in humans in Colombia. The differential identification of species should be done in risk groups and in areas where the circulation of this mycobacterium in cattle is known.

Palavras-chave : Mycobacterium bovis; Mycobacterium tuberculosis; tuberculosis; zoonosis; public health; Colombia.

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