Abstract

MEDINA, Miguel Ángel; MEYER, Wendy; ECHEVERRI, Carolina  and  BUILES, Natalia. Langerhans cell histiocytosis: Case report and literature review. Biomed. [online]. 2021, vol.41, n.3, pp.396-402.  Epub Sep 22, 2021. ISSN 0120-4157.  https://doi.org/10.7705/biomedica.5430.

Histiocytosis comprises a heterogeneous group of inflammatory diseases whose main cellular components are dendritic cells and macrophages. The inflammatory infiltrate can affect the skin and other organs and the clinical outcome varies from mild to fatal depending on the involved cell subset and multisystemic compromise. Delay in diagnosis may occur due to its non-specific presentation and to a low suspicion on the part of the clinician. We report the case of an infant who despite multiple consultations with nonspecific but characteristic symptoms of the disease was only finally diagnosed thanks to histopathological findings.

Keywords : Histiocytosis, Langerhans-cell; histiocytosis; pediatrics; conjunctivitis; dermatitis, seborrheic.

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