Abstract

OROZCO-SEBA, Beatriz E. et al. Intrahepatic cholestasis due to Treponema pallidum in an immunocompetent patient. Biomed. [online]. 2023, vol.43, n.2, pp.164-170.  Epub June 30, 2023. ISSN 0120-4157.  https://doi.org/10.7705/biomedica.6630.

Hepatitis due to Treponema pallidum is a rare entity and its diagnosis represents a clinical challenge. Treponema pallidum should be considered as a presumptive etiology in all patients with acute liver disease, when other frequent causes have been ruled out.

We present the case of a young, immunocompetent patient with elevated values in his liver tests, a cholestatic pattern, and maculopapular lesions on his palms and soles. Given his clinical picture, diagnostic tests, and response to the antimicrobial therapy, a diagnosis of cholestasis due to secondary syphilis has been established. It is important to include secondary syphilis within the possible causes of acute liver disease.

Keywords : Treponema pallidum; syphilis; cholestasis; therapeutics.

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