Abstract

TAVARES, Emanuele N et al. In vitro EVALUATION OF THE ANTIBACTERIAL AND MODULATORY ACTIVITIES OF CORN AND SOY FIXED OILS. Acta biol.Colomb. [online]. 2015, vol.20, n.1, pp.27-30. ISSN 0120-548X.  https://doi.org/10.15446/abc.v20n1.40764.

Nowadays, it is widely known that resistant pathogenic strains are becoming one of the greatest health problems related to human sciences. It is also known that fatty acids can present antimicrobial activity. The corn and soy oils are rich in fatty acids. In this regard, this work aimed to evaluate antibacterial and modulatory activity of these two industrial fixed oils. Both tests were performed using the microdilution method to Minimum inhibitory concentration under 1024 mg/ml. The aminoglycosides activity was enhanced by combining corn oil using E. coli 27. One of the mechanisms that might explain the synergism toward the corn oil, in part, might be due to the hidrophobic nature of the saturated and unsaturated lipids present in the sample. The results indicate that fixed oils might play a role as an alternative way to potentiate of the antimicrobial drugs.

Keywords : antibacterial activity; corn oil; modulation; soy oil.

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