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Acta Biológica Colombiana

Print version ISSN 0120-548X

Abstract

GOMEZ, Arlen Patricia; BELTRAN, Magda; ALVAREZ-MIRA, Diana Marcela  and  RAMIREZ-NIETO, Gloria Consuelo. Identification of genogroups of Infectious Bursal Disease Virus in poultry farms at Colombia. Acta biol.Colomb. [online]. 2019, vol.24, n.3, pp.463-473. ISSN 0120-548X.  http://dx.doi.org/10.15446/abc.v24n3.79369.

Infectious Bursal Disease Virus (IBDV) is an avibirnavirus with a dsRNA genome, which has a high mutation and recombination rates. Despite the immunosuppressive effect in poultry and the frequency of infections by this agent, few studies in Colombia that characterize the clinical signs and identify the circulating genogroups have been reported. This study aimed to determine the frequency of histopathological lesions in immune organs and to identify IBDV genogroups in poultry from Colombia. In this way, the Laboratorio de Patología Aviar (LPA) databases from the Universidad Nacional de Colombia (period 2016-2018) were analyzed in order to identify the frequency of lesions present in immune organs. 35 samples of the bursa of Fabricius, positive by RT-PCR, were sequenced to the gene that codes for the VP2 protein. 97 (25 %) cases showed microscopic lesions in the immune organs. The genogroups identified and the frequencies were: genogroup 1-69 % (classical viruses), genogroup 2-25 % (antigenic variants), and genogroup 4-6 % (identified in South America). These findings demonstrate the lesions of immune organs and the presence of different genogroups circulating in commercial birds in Colombia. This indicates the need to continue with these studies in order to have a better understanding of the infection in the field and to guide the design and implementation of control strategies.

Keywords : Bursa of Fabricius; diagnosis; immunosuppression; poultry; VP2.

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