Abstract

MENDOZA MEZA, Dary Luz; ROA MERCADO, Carlos  and  AHUMADA BARRAZA, César. The effects of soybean isoflavones over the bone health of adult and children. Salud, Barranquilla [online]. 2015, vol.31, n.1, pp.138-152. ISSN 0120-5552.

The soy isoflavones are secondary metabolites known as phytoestrogens because of its structural similarity to 17b-estradiol. Genistein and Daidzein are the main soy isoflavones. Due their binding ability to estrogen receptors (ER) they are considered as selective estrogen receptor modulators (SERM). The dietary intake of isoflavones has been associated with decreasing menopause symptoms, prevention of cardiovascular disease and some chronic diseases such as diabetes mellitus. Also, the isoflavones have been proposed for the treatment of certain kind of cancer and osteoporosis prevention, but there is a lot of controversy about the possible estrogenic effects in pubertal and prepubertal children who have been fed with soy protein-based formulas. The aim of this research is to present a systematic review of the soy isoflavone chemistry and their effects on bone health in adults and children.

Keywords : Soy isoflavones; genistein; daidzein; bone health.

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