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Revista Salud Uninorte

Print version ISSN 0120-5552On-line version ISSN 2011-7531


PENUELA-EPALZA, Martha Elena et al. Risk factors for surgical-site infection in the atlantic state, colombia. A case-control study. Salud, Barranquilla [online]. 2018, vol.34, n.1, pp.97-108. ISSN 0120-5552.


To evaluate sociodemographic, clinical and health-service-related determinants associated to surgical site infections in patients undergoing appendectomy in third level Hospitals, located in the Colombian Northern Region, from 2009 to 2013.


Retrospective data was collected of hospital records from participating hospitals; 80 cases and 272 controls were compared regarding socio-demographic (age, gender, regime of affiliation to the social-security health system), clinical (comorbidity, prior hospitalization, degree of appendix), and healthcare-related variables (diagnostic time, preoperative time, operation duration, prophylaxis with antibiotics and hospital-stay length). Both bivariate and multivariate analysis were conducted. Odds Ratios, 95% confidence intervals were estimated; Besides, both X2-Test and T Student Tests were used to evaluate statistical significance.


Socio-demographic (age, affiliation to the subsidized-health-system), clinical (metabolic disease) and health-care related factors such as preoperative waiting time showed to be associated to surgical site infections, in the bivariate analysis. In the final regression model only age above 54 (OR= 5,37); subsidized affiliation to the social security system (3,49) and histopathological grade of appendix, which included focal inflammation, epithelial ulcers, and isolated micro-abscesses in lymphatic’s follicles showed to be independent risk factors (OR= 1,98).


This study adds new evidence on the multifactorial origin of post-surgery nosocomial infections and spotlights health inequality as a major risk factor that needs to be addressed.

Keywords : Appendectomy; surgical wound infection; Clinical Factors; Case-Control; health inequality; subsidized health system; nosocomial infections; Colombia..

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