Objectives:

The objective of this study was to evaluate Vitamin D (VD) status and its association with disease severity in critically ill pediatric patients.

Methods:

An observational follow-up study was conducted on a prospective cohort of pediatric patients admitted to the intensive care units (ICU) of two health institutions. All admitted patients underwent measurement of 25-OH-VD, which were categorized as deficiency, insufficiency, or normal. The outcome variables were mechanical ventilation, the need for inotropes, renal replacement therapy, and mortality.

Results:

One-hundred seventy-five pediatric patients were followed up. The mean VD was (25.43 mg/dl, SD = 10.17). The prevalence of deficiency was 26.29 % (n= 46), and for insufficiency, 48 %. Patients with VD deficiency (adjusted RR 2.07 CI95 1.12 - 3.82) had a higher risk of requiring inotropes.

Conclusion:

VD deficiency was associated with the need for inotropic medication during ICU stay.

        · resumo em Espanhol     · texto em Inglês     · Inglês ( pdf )