Abstract

URIBE, Carlos E et al. Alergia al clopidogrel: hipersensibilidad con exantema y neutropenia, reporte de dos casos y revisión de la literaturaAllergy to clopidogrel: hypersensibility with exanthema and neutropenia: report of two cases and literature review. Rev. Col. Cardiol. [online]. 2007, vol.14, n.5, pp.299-307. ISSN 0120-5633.

Clopidogrel is actually one of the most common used inhibitors of platelet aggregation in cardiology and its use is being increased since its introduction in the clinical practice. Allergy to this medicine is rare. As it is now more currently used and is considered essential in the prophylaxis of stent thrombosis, when allergy supervenes, the physician faces a dilemma difficult to solve, because in these patients with medicated stents, its suspension could be catastrophic. In this article, two cases of hypersensitivity to clopidogrel are described. Review of literature and of the available options for treating this allergy and of the protocols of desensitization to this medicine is done.

Keywords : clopidogrel; allergy; exanthema; neutropenia; desensitization.

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