SciELO - Scientific Electronic Library Online

 
vol.15 issue3Prevalence and behaviour of risk factors in metabolic syndrome according to different age intervals, in a female cohort of the area of influence of the Clínica de las Américas in Medellín, ColombiaTreatment of refractory chest angina with spinal electrical stimulator: literature review author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista Colombiana de Cardiología

Print version ISSN 0120-5633

Abstract

BARRERA, María del P et al. Metabolic syndrome: an interdisciplinary outlook. Rev. Col. Cardiol. [online]. 2008, vol.15, n.3, pp.111-126. ISSN 0120-5633.

The metabolic syndrome is characterized by the presence of alterations such as insulin resistance manifested by hyperinsulinism and its association with pathologies like obesity, diabetes mellitus type 2, arterial hypertension and dyslipidemia. There are other risk factors like overweight, obesity, high carbohydrate and fat intake, cigarette smoking and sedentary life style. Several different groups have reviewed the metabolic syndrome concept: the World Health Organization, the European Group for the Study of Insulin Resistance, the American College of Clinical Endocrinology, the Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults and the International Diabetes Federation. Different prevalence values are reported by epidemiologic studies depending on the population studied and on the diagnostic criteria; nevertheless, all of them depict an important public health problem. The core of the syndrome alterations resides in the insulin resistance that comprises a pro-inflammatory state that diminishes insulin capacity to act in the target organs. The visceral adipose tissue synthesizes big amounts of hormones and interleukins that influence the associated metabolic alterations. Primary and secondary preventive measures are necessary in order to diminish morbimortality and by this, achieve important effects in society and in the individuals’ life quality. The treatment considers non-pharmacologic aspects and prescription of medicines when necessary. The pharmacologic treatment must consider the control of cardiovascular risk factors.

Keywords : metabolic syndrome; insulin resistance; cardiovascular disease; diagnostic criteria; prevalence; prevention; treatment.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License