Abstract

GARCIA G, Ronald G  and  LOPEZ-JARAMILLO, Patricio. Use of aspirin in the prevention of cardiovascular diseases. Rev. Col. Cardiol. [online]. 2008, vol.15, n.5, pp.223-230. ISSN 0120-5633.

During the last few years multiple studies have demonstrated that aspirin administration is effective in reducing the risk of coronary artery disease and ischemic cerebrovascular disease in men and women respectively. The benefit of receiving low-dose aspirin (75-160 mg/d) clearly overcomes the risk of hemorrhagic complications in subjects with a coronary heart disease risk of >=1% per year (>=10% in 10 years). Despite this evidence, the use of low-dose aspirin as a primary prevention strategy is not fully established yet. The application of the current recommendations of aspirin use in primary prevention could be beneficial in the Colombian population, especially because evidence shows a greater susceptibility to present high levels of chronic low-degree inflammation associated to a greater cardiovascular risk in our population. However, further studies are needed to confirm this hypothesis.

Keywords : aspirin; prevention; risk-benefit; coronary artery disease; inflammation.

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