Abstract

JARAMILLO, Carlos J; PERDOMO, Luis F; CARDONA, Esteban  and  LONDONO, Gabriel A. Brugada syndrome in a patient with syncope: A case report and literature review. Rev. Colom. Cardiol. [online]. 2010, vol.17, n.4, pp.177-186. ISSN 0120-5633.

Brugada syndrome is a sporadic autosomal dominant genetic disease that affects cardiac sodium channels. It is clinically characterized by recurrent syncope and/or sudden death with electrocardiographic manifestations that simulate a right bundle branch block accompanied by ST-segment elevation in the right precordial leads (V1, V2 and V3) without structural cardiac changes. It mainly affects men in their fourth decade and is most prevalent in southwestern Asia. We present the case of a patient with history of syncope, type-2 Brugada electrocardiographic pattern and who has a brother also with history of syncope. The patient had a positive tilt test for neurocardiogenic syncope. He was diagnosed as neurocardiogenic syndrome, without discarding the initial suspicion of Brugada syndrome.

Keywords : Brugada syndrome; syncope; sudden death; arrhythmias; Brugada-type electrocardiographic patterns; cardiac sodium channels; sodium channel blockers.

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