SciELO - Scientific Electronic Library Online

vol.18 issue5Chagas disease: clinicopathologic correlation. Series of cases of the University Hospital of Santander - Department of Pathology, Universidad Industrial de SantanderPrognostic value of C-reactive protein in patients with acute myocardial infarction undergoing percutaneous coronary intervention author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand



Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista Colombiana de Cardiología

Print version ISSN 0120-5633


MERCHAN, Alonso; JARAMILLO, Claudia; MENDOZA, Fernán  and  AGUDELO, Juan Fernando. Goals on the lipid profile of people with previous coronary artery disease are being achieved?. Rev. Colomb. Cardiol. [online]. 2011, vol.18, n.5, pp.262-267. ISSN 0120-5633.

Objectives: to verify the level of compliance with the targets in LDL cholesterol, non-HDL cholesterol, triglycerides, HDL cholesterol, in accordance with the recommendations of the NCEP-ATPIII guide and current recommendations in a population of patients hospitalized for non-cardiovascular causes but with a history of coronary disease. Analyze also lipid-lowering drugs used by this population as well as the prevalence of metabolic syndrome, abnormal fasting glucose and type 2 diabetes mellitus. Methodology: the percentage of fulfillment of these goals was assessed using the STATA statistical analysis program. Findings of the lipid profile were compared with the proposal from the NCEP-ATPIII guide and current recommendations (primary endpoint). Similarly, lipid-lowering drugs used were analyzed as well as the prevalence of abnormal fasting glucose, diabetes mellitus type 2 and metabolic syndrome (secondary endpoint). Results: we identified 281 patients who met the inclusion criteria. Table 2 summarizes the results of the primary endpoint. According to the NCEP-ATPIII, in high risk, the percentage of patients who met the LDL cholesterol goals (main goal in the treatment of dyslipidemias), was 57,2% and in the very high risk, 23,5%. Currently, patients with coronary heart disease independent of the presence of metabolic syndrome or diabetes mellitus, a goal for LDL cholesterol below 70 mg/dL is recommended (Recommendation IIa); this was observed in 21.7% of patients studied. The prevalence of abnormal fasting glucose was 25.6%, that of type 2 diabetes mellitus was 20% and that of metabolic syndrome 45.2%. With respect to lipid-lowering drugs used, we observed that 56% used lovastatin, 14% did not use lipid-lowering drugs and none had any association of these drugs. Conclusions: after nine years of the publication of NCEP-ATPIII guidelines and subsequent recommendations on the goals of the lipid profile in patients with coronary disease and despite the dissemination of these through lectures, conferences and publications, these goals are met by a low percentage of patients, as evidenced by this observational study in patients hospitalized for causes other than coronary heart disease but with this history. One explanation for this poor performance is the use of lovastatin, that is a low efficacy statin to reduce LDL cholesterol. Other possible causes are analyzed and proposals to achieve the objectives are made.

Keywords : lipid profile goals; coronary heart disease; high risk of coronary events; LDL-c; HDL-c; triglycerides; non-HDL cholesterol.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License