SciELO - Scientific Electronic Library Online

vol.18 issue5Prognostic value of C-reactive protein in patients with acute myocardial infarction undergoing percutaneous coronary interventionProgressive familial atrio-ventricular block type I: clinical description of a family author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista Colombiana de Cardiología

Print version ISSN 0120-5633


MANZUR, Fernando; ALVEAR, Ciro  and  ALAYON, Alicia Norma. Role of C-reactive protein in cardiovascular diseases. Rev. Colomb. Cardiol. [online]. 2011, vol.18, n.5, pp.273-278. ISSN 0120-5633.

C-reactive protein (CRP), a sensitive marker of inflammation is an independent predictor of future cardiovascular disease (CVD), which is one of the main causes of death worldwide. The role of inflammation in cardiovascular disease has been well documented in the last decade, and inflammation has been demonstrated in all stages of atherosclerosis, from its beginning and growth to the plaque rupture. CRP is an acute phase protein, highly sensitive as a marker of general inflammation. The presence of CRP has been determined in experimental studies in arteries with atherosclerotic lesions. It has been demonstrated as well that CRP induces directly the production of other inflammatory cells and decreases the expression of nitric oxide synthase. This means that from the biological standpoint CRP takes part in the atherogenic process. In adults, CRP detected through high sensitive CRP-test (hs-CRP) is associated to traditional risk factors and its concentration predicts cardiovascular events.

Keywords : C-reactive protein; risk factors; adiposity; obesity.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License