Abstract

RAMIREZ-VELEZ, Robinson. Relationship between vascular shear stress and flow-mediated dilation in healthy pregnant women. Rev. Colomb. Cardiol. [online]. 2011, vol.18, n.6, pp.324-329. ISSN 0120-5633.

Flow-mediated vasodilation (FMV) is a physiological measure to non-invasively estimate endothelial function. Similarly, it is associated with some cardiovascular risk factors and cardiovascular events. The aim of this study is to present the first exploration of the standardization of FMV data during pregnancy and examine the relationship of endothelial friction stress (EFE) and the normalization of flow-mediated vasodilation (nMFV) in this population. A relationship between VMF and nVMF (R2 = 0.782, p <0.05) was found, but not between the VMF and the EFE (R2 = 0.782, p> 0.05) or between the EFE and nVMF (R2 = 0.013, p> 0.05). Future research, carefully designed, could examine this proposal in different populations. We suggest that MFV and nMFV, may ever be seen as tools with clinical applications to estimate cardiovascular risk.

Keywords : pregnancy; endothelial function; shear stress.

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