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Revista Colombiana de Cardiología

Print version ISSN 0120-5633


MORENO, Nelson L. Cardiac conditioning: "beyond reperfusion". Rev. Colomb. Cardiol. [online]. 2013, vol.20, n.4, pp.223-229. ISSN 0120-5633.

The potential damage associated with reperfusion, which could explain up to 50% of the total area infarcted was described over fourty years ago. An innate mechanism of protection against ischemia-reperfusion injury was described in the late 80's which was called ischemic conditioning. Not just various types of conditioning have been described in the last decades, but also human clinical experiments with encouraging initial results in the reduction of the infarcted area have been conducted. However, it is not still demonstrated whether the reduction of reperfusion injury has an impact on mortality. The current research will allow to clarify this unanswered question in the near future.

Keywords : reperfusion; ischemic heart disease; acute myocardial infarction.

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