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Revista Colombiana de Cardiología

Print version ISSN 0120-5633


CASTRO TORRES, Yaniel et al. Vitamin D deficiency and hypertension. Supporting evidence. Rev. Colomb. Cardiol. [online]. 2016, vol.23, n.1, pp.42-48. ISSN 0120-5633.

Vitamin D deficiency has been related with a rise in blood pressure values. An increase in renin-angiotensin-aldosterone system activity, endothelial dysfunction, calcium homeostasis modifications, a rise in oxidative stress and reduction in prostaglandins production appear to be the main pathophysiological mechanisms associated in patients with low vitamin D levels and high blood pressure values. The use of supplements of vitamin D for reducing the risk or progression of hypertension could be a choice for patients with low levels of this vitamin. Low levels of vitamin D have been related with a failure in antihypertensive treatment, and further evaluation of efficacy of antihypertensive treatment in patients with low levels of this substance should be continued.

Keywords : Arterial hypertension; Risk factors; Renin; Angiotensin.

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