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Revista Colombiana de Cardiología

Print version ISSN 0120-5633


IDIAZABAL, Uxua et al. Transthyretin amyloidosis: Scintigraphy showing the way. Rev. Colomb. Cardiol. [online]. 2016, vol.23, n.1, pp.71.e1-71.e5. ISSN 0120-5633.

Background and objetive: Cardiac amyloidosis is a very severe disease caused by extracellular deposition of insoluble fibrils. The gold standard for diagnosing cardiac amyloidosis is an endomyocardial biopsy. This technique is invasive, limited to experienced centers, and thus not widely available. It is required to perform special techniques to precisely determine the amyloid type as the treatment, evolution and prognosis of the disease differs greatly according the type of amyloid present. Method: In this case report we want to present the difficulties for diagnosing the types of amyloid involved in cardiac amyloidosis as well as the usefulness of cardiac MRI for diagnosing cardiac amyloidosis, particularly when performed with the use of the gadolinium as an imaging agent. Results: Biventricular, concentric late gadolinium enhancement on cardiac magnetic resonance and on technetium pyrophosphate scan (99mTc-DPD) showed to be helpful in the diagnosis of senile cardiac amyloidosis transthyrenin variant.

Keywords : Cardiac amyloidosis; Radioisotopes; Magnetic resonance.

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