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Revista Colombiana de Cardiología

Print version ISSN 0120-5633

Abstract

GOMEZ, Ricardo et al. Factors associated with presence of bleeding classified by Bleeding Academic Research Consortium in patients with acute coronary syndrome undergoing percutaneous coronary intervention. Rev. Colomb. Cardiol. [online]. 2017, vol.24, n.1, pp.15-25. ISSN 0120-5633.  http://dx.doi.org/10.1016/j.rccar.2016.04.013.

Background and objectives:

Bleeding is the main non-cardiac complication related to percutaneous coronary intervention and it is associated to an increase of the risk of adverse events. Nowadays there are multiple scales to define risk of bleeding and several definitions for bleeding. The goal is to determine factors associated to the presence of bleeding in patients with acute coronary syndrome undergoing percutaneus coronary intervention, using the the Bleeding Academic Research Consortium scale to then issue recommendations.

Material and methods:

Case-control analytical observational study in patients with acute coronary syndrome undergoing percutaneous coronary intervention applying the Bleeding Academic Research Consortium scale. Cases were defined by patients who presented bleeding following the surgery (Bleeding Academic Research Consortium type 1-5) and controls by patients who did not show bleeding (Bleeding Academic Research Consortium type 0).

Results:

366 were selected (121 cases, 245 controls). 33% of the patients showed some type of bleeding, divided into: type 1: 12%; type 2: 13.4%; type 3: 7.3% and type 5: 0.3%. Multivariate analysis of most important predictive factors for bleeding that were statistically significant were: female gender, warfarin treatment and use of Tirobifan during percutaneus coronary intervention.

Conclusions:

Bleeding is a frequent event during percutaneus coronary intervention. According to the Bleeding Academic Research Consortium classification, most bleedings were of types 1 and 2. Risk factors for bleeding described worldwide are similar to those of this study. Female gender, warfarin treatment and use of Tirobifan were statistically significant. Bleeding Academic Research Consortium scale is considered a good indicator to define bleeding types.

Keywords : Acute coronary syndrome; Bleeding; Percutaneous coronary intervention..

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