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Revista Colombiana de Cardiología

versión impresa ISSN 0120-5633

Resumen

RUZ-MONTES, Miguel A. et al. More frequent congenital cardiopathies in children with Down síndrome. Rev. Colomb. Cardiol. [online]. 2017, vol.24, n.1, pp.66-70. ISSN 0120-5633.  http://dx.doi.org/10.1016/j.rccar.2016.06.014.

Introduction:

Down’s syndrome is most common chromosomal alteration amongst humans, and it is mostly associated to congenital heart diseases, the main cause of mortality during the first

years of life.

Motivation:

To describe the frequency of each congenial heart disease and their clinical characteristics in children with Down’s syndrome at the Cardio VID Clinic in Medellín.

Methods:

Observational, cross-sectional, descriptive study conducted in the Cardio VID Clinic with patients diagnosed with Down’s syndrome and congenital heart diseases between January

1st 2010 and December 31st 2013.

Results:

99 patients meeting all selection criteria were selected, with an average age of 8.1 months, 52 (52.5%) female. According to their medical records, the most common congenital

heart diseases in children with Down’s syndrome were perimembranous ventricular septal defect in 61 cases (61.6%), atrial septal defect in 46 (46.5%) and ductus arteriosus in 38 (38.4%).

Conclusion:

To our knowledge it is the first epidemiological study regarding the frequency and type of congenital heart diseases found in Colombian children with Down’s syndrome in a cardiovascular

centre. The high frequency of ventricular septal defect and differential distribution of heart defects associated with Down’s syndrome in the population differ to the data reported in other studies.

Palabras clave : Congenital heart disease; Ventricular septal defect; Pulmonary arterial hypertension; Heart failure.

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