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Revista Colombiana de Cardiología

Print version ISSN 0120-5633


ALARCON-GARCIA, José Carlos; RODRIGUEZ-SUAREZ, Santiago; GARCIA-OCAA, Paula  and  GARCIA-MORILLO, J. Salvador. Acute Coronary Syndrome in Erdheim-Chester. Etiopathogenesis and therapeutic Implications. Rev. Colomb. Cardiol. [online]. 2017, vol.24, n.3, pp.298-298.  Epub Aug 01, 2016. ISSN 0120-5633.

Erdheim-Chester disease is a non-Langerhans cell histiocytosis of uncertain origin. It is characterized by multiorgan involvement due to infiltration of CD68+/CD1a- histiocytes, in the form of xantogranulomas, most commonly affecting the metaphysis and diaphysis of long bones. The diagnosis is made by biopsy showing CD68+/CD1ahistiocytes, lack of S protein and Birbeck granules. Cardiovascular involvement is underestimated. We report a case of a 67 year-old man with Erdheim-Chester disease and acute myocardial infarction due to coronary involvement, in addition to bone, vascular, pituitary and retroperitoneal disease. We review relevant literature and describe the clinical management of these patients.

Keywords : Angiography; Treatment; Coronary disease.

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