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Revista Colombiana de Cardiología

Print version ISSN 0120-5633


ARROYAVE, Jorge A. et al. Frequent premature ventricular complexes following ablation of atrial fibrillation and their relationship to the autonomic tone measured with Holter parametres. Rev. Colomb. Cardiol. [online]. 2017, vol.24, n.4, pp.361-368.  Epub Mar 02, 2017. ISSN 0120-5633.


Radiofrequency catheter ablation is a promising treatment for atrial fibrillation.

Despite its security, and increase in the frequency of premature ventricular complexes and nonsustained ventricular tachycardia has been evidenced, which could have autonomic influences.


To analyse autonomic activity using Holter monitoring parametres in patients who underwent this procedure.


Retrospective analysis of patients with frequent premature ventricular complexes following electric isolation of pulmonary veins due to atrial fibrillation, followed up with Holter monitorisation between October 2010 and November 2014 with the goal of comparing heart rate variability parametres.


12.4% had a significant increase of ventricular automacity. Demographic data in compared groups did not reveal statistically significant differences. The average of premature ventricular complexes within 24 hours was of 5,363, with 237 per hour. In the study group, 65% showed non-sustained ventricular tachycardia. Heart rate variability was lower in patients from the control group (p = 0.000). Evaluation of spectral frequency evidenced a decrease in LF and HF for both groups, with a lower value for the control group (p = 0.000). HF/LF relationship for both groups was high (p = 0.612).


Ablation of pulmonary veins in the treatment of atrial fibrillation can lead to the development of frequent premature ventricular complexes and ventricular tachycardia. The impact on the parasympathetic and sympathetic system could be a factor that triggers this condition.

Keywords : Atrial fibrillation; Autonomic nervous system; Tachyarrhythmia; Catheter ablation.

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