Abstract

OCAMPO-SALGADO, Carolina; DUQUE-RAMIREZ, Mauricio; MARIN-VELASQUEZ, Jorge Eduardo  and  SERNA-POSADA, María del Mar. Endocarditis due to Escherichia coli of a native valve associated with implantable cardiac devices. Rev. Colomb. Cardiol. [online]. 2018, vol.25, n.2, pp.145-150. ISSN 0120-5633.  https://doi.org/10.1016/j.rccar.2017.12.020.

Bacterial endocarditis is a disease with high morbidity and mortality, and is mainly caused by gram positive cocci, less frequently due to organisms of the HACEK group (Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, Kingella), and unusually by other bacteria. Escherichia coli is the principal cause of nosocomial bacteraemia, but there are no more than 50 cases reported in the literature of due to this microorganism. The genitourinary tract is the usual sources of infectious compromises favoured by risk factors such as, diabetes mellitus, structural heart disease, history of malignancy, use of intravenous drugs, prosthetic material, and advanced age. E. coli in native valves have tropism for valves of the left side. Furthermore, unusual presentations have been described as regards prosthetic material and resistant organism, although it is much more common to find wild strains. Endocarditis due to E. coli is strongly associated with local complications, and a need for surgical management. The phylogenetics of the E. coli isolated in endocardial infections, and the virulence factors that enable it to adhere to this tissue whether in the presence or not of prosthetic material, has been widely discussed. A case is presented of endocarditis associated with a pacemaker electrode due to E. coli, followed by a review of the available literature on this disease.

Keywords : Cardiac device; Escherichia coli; Endocarditis; Native valve.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )