Abstract

ARAGON, Diana; RIVERA, María Fernanda  and  LIZCANO, Fernando. Role of the fat cell in cardiovascular risk. Rev. Colomb. Cardiol. [online]. 2020, vol.27, n.6, pp.576-581.  Epub Aug 03, 2021. ISSN 0120-5633.  https://doi.org/10.1016/j.rccar.2020.04.007.

Obesity is a chronic non-transmissible disease that has recently had a special connotation due to the increase of its prevalence in developing countries. The increase in obesity is related to an expansion in the appearance of metabolic diseases and cardiovascular risk. Although the prevalence of obesity is increasing in all countries of the world, there are regional differences in both the prevalence and trends of obesity. Therefore, understanding the circumstances of these regional differences could help provide guidance for the most promising intervention strategies. Despite being considered a simple outcome in a proportion of what is ingested and what is spent, there are many factors that regulate this disease. It is not easy to find therapeutic measures for obesity, because their causes are multiple. Recently, the functional characterization of adipocytes, especially Beige adipocytes, has been of particular interest since their function is intimately related to the external circumstances of the environment and they have a flexibility that allows them to produce energy and improve many of the metabolic parameters in individuals. In the present manuscript we will focus on the characteristics of fat cells and their influence on cardiovascular risk.

Keywords : Obesity; Cardiovascular risk; White adipocyte; Beige adipocyte; Brown adipocyte.

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