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Revista Colombiana de Cardiología

Print version ISSN 0120-5633

Abstract

PEREZ DIAZ, Pedro et al. Circulating markers of inflammation and severity of coronary atherosclerosis in acute coronary syndrome: Prospective observational study in a general university hospital. Rev. Colomb. Cardiol. [online]. 2020, vol.27, n.6, pp.630-636.  Epub Aug 04, 2021. ISSN 0120-5633.  https://doi.org/10.1016/j.rccar.2019.11.007.

Objective:

To determine whether there is a relationship between C - reactive protein and fibrinogen levels and the extent of atherosclerosis in acute coronary syndrome.

Methods:

A prospective observational study was conducted that include 873 patients with coronary syndrome treated in a hospital between the years 2016 and 2018. An analysis was made that included C - reactive protein and fibrinogen levels, metabolic markers, extent of coronary atherosclerosis.

Results:

No positive correlation was found between the C - reactive protein and fibrinogen levels and the metabolic markers, nor with one, two, or three vessel disease (P=.829; P=.810).

Conclusions:

Although blood C-Reactive Protein and fibrinogen levels are associated with the rate of cardiovascular events, this study was unable to demonstrate whether there is a relationship between these and the severity of the coronary atherosclerosis.

Keywords : C - reactive protein; Fibrinogen levels; Atherosclerosis; Coronary arterial disease.

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