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Revista Colombiana de Cardiología
Print version ISSN 0120-5633
Abstract
RAMIREZ-RAMOS, Cristhian F. et al. Endomyocardial fibrosis: an updated review, about some cases in a heart failure program. Rev. Colomb. Cardiol. [online]. 2021, vol.28, n.6, pp.530-538. Epub Jan 07, 2022. ISSN 0120-5633. https://doi.org/10.24875/rccar.m21000094.
Introduction
Endomyocardial fibrosis is one of the neglected cardiovascular disease, the main cause of restrictive cardiomyopathy. There are an estimated 10-12 million people with the disease worldwide. Most are restricted to areas of Africa, Asia and in Latin America in Brazil and Colombia. The etiology and pathophysiology are poorly understood. For its diagnosis, the patient’s data, the clinical picture and the echocardiographic findings must be taken into account. We present the confirmed cases in a cardiovascular referral center.
Description of the cases
Three cases have been documented of which two are women. All debuted with insidious dyspnea on exertion. The echocardiographic findings were diastolic dysfunction with a restrictive pattern, moderate atrioventricular valve insufficiency, and pulmonary hypertension. In two cases, endocardial abnormal images were found in the left ventricle and an endomyocardial biopsy was performed to confirm the diagnosis. None improved functional class or frequency of hospitalizations.
Conclusions
Endomyocardial fibrosis should be considered in a patient with heart failure with an associated restrictive pattern, and with little response to conventional pharmacological management. The patients presented had typical findings of the disease with the particularity of being older.
Keywords : Heart failure; Endomyocardial fibrosis; Eosinophilia; Restrictive cardiomyopathy.