Objective:

To analyze global disparities in research on the neurodevelopment and neuropsychology of congenital heart disease (CHD) in the past 20 years (2000-2019) and explore the association with its disability burden.

Method:

A bibliometric analysis of articles published between 2000 and 2019 in SCOPUS. Country-level data on disability-adjusted life years (DALYs per 100,000 persons) for CHD was obtained from the Global Burden of Disease Study-2019, and income group was obtained from the World Bank database.

Results:

The research output rate was 1.81 articles per million in high-income countries (HICs) and 0.07 in low- and middle-income countries (LMICs). Research output was 27 times higher in HICs than in LMICs (p < 0.001). In LMICs, the DALY rate was 5.2 (95% CI: 4.9-5.5) times higher than in HICs. We found a negative association between research productivity and the DALY rate (RR = 0.9; 95% CI: 0.8-0.9).

Conclusion:

We found similar disparity patterns by income group for research output and CHD disability burden. Countries with a higher CHD disability burden were less productive in this research field. To reverse this pattern, international collaboration and national strengthening strategies for research capacity building are required.

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