Introduction:

Cardiac neoplasms are rare, in a postmortem analysis they are described between 0.01 to 0.1%; However, metastases to the heart are not as uncommon as one might assume. Secondary involvement of the pericardium, myocardium, great vessels, or coronary arteries has been reported: 0.7 and 3.5% in general autopsies and up to 9.1% in patients with known malignancies.

Objective:

To know the sociodemographic, clinical and therapeutic findings of patients with hematolymphoid tumors metastatic to the heart.

Materials and methods:

The sociodemographic and clinical characteristics of the patients are described, and clinical outcomes. A review of the complete medical records, laboratories, and diagnostic images is performed. A review of the literature was carried out in the main databases: PubMed, Scopus, Google Scholar, Web of Science, EMBASE, and Scielo in Spanish and English. This article is under the guidelines of the 2016 CARE.

Results:

4 clinical cases of hematolymphoid neoplasia in the heart are presented. All 4 patients attended the hospital due to progressive dyspnea. Histopathology reported a B-cell precursor lymphoblastic lymphoma, high-grade pleomorphic angiosarcoma – high-grade malignant fibrous histiocytoma, non-Hodgkin lymphoma, and a high-grade angiosarcoma. All cases required surgery for cardiovascular complications such as cardiac tamponade or mass effect in the involved structures and chemotherapy and all patients had a good clinical outcome.

Conclusions:

Hematolymphoid tumors of the heart are rare. However, it is necessary to consider differential diagnoses for timely diagnosis and treatment since they can cause complications that can threaten the patient’s life.

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