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Revista Colombiana de Cardiología

Print version ISSN 0120-5633

Abstract

PINEDA-SANABRIA, Pablo et al. Prevalence and characterization of tetralogy of Fallot: a comprehensive study. Rev. Colomb. Cardiol. [online]. 2025, vol.32, n.1, pp.39-45.  Epub Mar 05, 2025. ISSN 0120-5633.  https://doi.org/10.24875/rccar.23000098.

Introduction:

Tetralogy of Fallot (TOF) is a congenital heart defect (CHD) with a global prevalence of 3.56 cases per 10,000 live births (LB), according to Liu et. al in 2019.

Objective:

to determine the prevalence and describe TOF cases in Bogotá, Colombia from 2015 to 2021.

Method:

a retrospective cross-sectional study was performed, based on data obtained from the Public Health Surveillance System database. Birth defects were classified according to the International Classification of Diseases (ICD-10), and cases were defined as all LB with TOF, with a birth weight superior to 500 grams.

Results:

he estimated prevalence for TOF was 2.21 cases (CI 1.85-2.61) per 10,000 LB, with a total of 137 cases. Maximum prevalence was observed in 2017, with 3.15 (CI: 2.11-4.53), and the lowest prevalence in 2015, with 1.26 (CI: 0.67-2.18) per 10,000 LB. The mean birth weight was 2575.9 g (SD: 660.5), and the average gestational age at birth was 35.85 weeks (SD: 3.95). The average maternal age was 29.1 years (SD: 7.05). The mortality rate was estimated at 17.51%. Regarding health insurance, 10.95% of cases were not affiliated with any regime. Down and Edwards syndromes were observed in 9 and 3 cases, respectively.

Conclusions:

the prevalence of TOF in our city was lower than that reported in current global estimates. Nonetheless, an increase with regard to previous local data was observed. This change in prevalence trends may be attributed to improvements in surveillance programs.

Keywords : Tetralogy of Fallot; Congenital heart defects; Birth defects; Congenital abnormalities; Epidemiology; Public health surveillance.

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