Abstract

PEMBERTHY LOPEZ, CAROLINA et al. Clinical and therapeutic aspects in the treatment of urinary tract infection. Structured review. CES Med. [online]. 2011, vol.25, n.2, pp.135-152. ISSN 0120-8705.

Objective: The urinary tract infections (UTI) are more frequent infection after respiratory infectious diseases. It is therefore considered necessary to have systematic and updated information to help improve drug therapy outcomes and reduce morbidity and mortality associated with this infection. The aim of this study was to perform a structured review of clinical and pharmacotherapeutic aspects of urinary tract infections. Methods: We conducted a structured review of urinary tract infection in PubMed/MedLine of articles published in English and Spanish, between 2007and 2010, in humans, with access to full text. Search terms were: "Urinary tract infections" AND (classification OR epidemiology OR complications OR physiology OR physiopathology OR drug therapy) in title/abstract field. The information was complemented both by a specific search of Colombia Scielo database, using the terms: urinary tract infections and urinary tract Infection, and by review of references cited in relevant articles. The information is organized into the following sections: Classification, epidemiological, risk factors, etiology, clinical presentation, diagnosis, drug therapy, prophylaxis and resistance. Relevant aspects are presented and current urinary tract infection (UTI) related to its classification, epidemiology, risk factors, etiology, clinical presentation, diagnosis, drug therapy, prophylaxis and antibiotic resistance. Results: We present some relevant and current aspects of the urinary tract infection related to its classification, epidemiology, risk factors, etiology, clinical presentation, diagnosis, drug therapy, prophylaxis, and antibiotic resistance. Conclusions: The review of health problems common in the population, such as the UTI, offers the ability of update and outline an approach based pharmacotherapy based on the proper use of medicines, in order to reduce the likelihood of treatment failure and resistance of microorganisms. In Colombia, the epidemiological and drug resistance data are scarce; thus it is necessary to design and to develop more studies with the goal to help generate comprehensive and updated information, including implementation of monitoring programs that help to define and develop recommendations and guidelines on the management

Keywords : Urinary tract infection; Clinical topic; Pharmacotherapeutic topic; Review.

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