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CES Medicina

Print version ISSN 0120-8705


MEDINA-ARANGO, ÁNGELA PIEDAD; VALENCIA-QUINTERO, LEIDY JOHANNA  and  ARREDONDO-OSSA, MARÍA ISABEL. Evaluation of the efficacy of a skin lightening gel product in volunteer diagnosed with melasma. CES Med. [online]. 2015, vol.29, n.1, pp.07-21. ISSN 0120-8705.

Introduction: Melasma is a common hyperpigmentation that primarily affects women compromising their aesthetic perception and self-esteem, with a significant impact on their psychological, social and cultural environment. Multiple treatments have been proposed with apparent effectiveness; however, some products have been associated with numerous cutaneous and systemic complications that have generated that are stricter regulations for the preparation and distribution of this type of treatment. Objective: To determine whether the use of a skin lightening gel product helps in clearance of melasma. Methodology: By uncontrolled open design nonrandomized, instrumental evaluations were performed using a Mexameter®in a treated area (with melasma) and other control (without melasma) on day 1 and at 15, 30 and 60 days postapplication started. Results: After 60 days of application of the product under normal conditions of use in a panel of 30 volunteers diagnosed with melasma, it showed a statistically significant reduction in instrumental measurements of melanin index of 340.1 ± 111 at baseline to 288.5 ± 85.4 in the eighth week. In assessing the perception of the volunteers, 72.4 % reported a very good skin lightening effect, 89.7 % saw additional benefits like more hydrated skin, smoother, softer, 82.8 % liked the product and 96.6 % would use it. Conclusion: This study showed the skin-lightening efficacy of the Emclarex®product since it showed a 57.7 % decrease in melanin index in 89.7 % of the volunteers diagnosed with melasma, after 60 days of use.

Keywords : Efficacy; Melanin; Melasma Treatment; Phyllanthus emblica.

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