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CES Medicina

Print version ISSN 0120-8705

Abstract

MADRIGAL-CADAVID, Juliana  and  AMARILES, Pedro. Incompatibility of intravenous drugs: Structured review. CES Med. [online]. 2017, vol.31, n.1, pp.58-69. ISSN 0120-8705.  http://dx.doi.org/10.21615/cesmedicina.31.1.6.

Introduction:

The physical or chemical incompatibilities between mixtures of intravenous drugs may compromise the efficacy and safety of treatment and the patient. The availability of information related to this aspect is limited or fractionated, which restricts its use; in this context. The objective of the present study was to compile in a table the available information in the databases on the compatibility/incompatibility between intravenous drugs, which favors the processes of prescription, preparation and administration of these products.

Methods:

We completed a structured review of incompatibilities of intravenous drugs in PubMed/Medline using the MeSH terms: Drug Incompatibility, Administration Intravenous, and Infusions Intravenous, we collected articles in English or Spanish, with access to full text until February 29, 2016. We identified 121 articles, from which we selected 58; additionally we included 18 manuscripts of the references considered as important.

Results:

With the information obtained was structured a table on compatibility/incompatibility of 100 intravenous drugs, the time of stability, conditions of storage, type of compatibility/incompatibility presented and the type of management recommended.

Conclusion:

We arranged information on compatibility/incompatibility of drugs, which may improve the processes of prescription, preparation and administration by the health care professionals, so it could contribute to the effectiveness and safety of these drugs.

Keywords : Drug Incompatibility; Intravenous administration; Intravenous infusions.

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