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CES Medicina

Print version ISSN 0120-8705

Abstract

OCAMPO-PALACIO, Alejandro et al. Prescription of antibiotics in infections of the skin and soft tissues. CES Med. [online]. 2018, vol.32, n.1, pp.3-13. ISSN 0120-8705.  http://dx.doi.org/10.21615/cesmedicina.32.1.

Introduction:

Infections of skin and soft tissues are common in clinical practice, which may even be responsible for sepsis and severe complications.

Objective:

To describe the prescription of antimicrobials and variables associated with their use in patients with diagnosis of infections of skin and soft tissues in a primary care hospital.

Materials and Methods:

Cross-sectional study in patients hospitalized for infections of the skin between 1 January and 31 December 2014. A simple random sampling was performed. Were included sociodemographic, clinical and pharmacological variables from medical records. Treatment was defined as adequate when there was a correlation between the diagnosis of each patient according to the International Classification of Diseases (ICD-10) as purulent or non-purulent infection, severity (mild, moderate or severe) and prescribed medication. Multivariate analysis using. SPSS 22.0.

Results:

A total of 309 patients were included, and the penicillins corresponded to the initial most formulated antibiotics (81.7 % of cases); 231patients (74.8 %) had well indicated antibiotic treatment. Comorbid conditions most frequently found in patients of this cohort were antiinflammatory drugs (NSAIDs) (61.2 %). Receiving the first oral antibiotic was less likely that the prescription was inadequate (OR:0.215;IC95 %:0.115-0.400).

Conclusion:

The data obtained should be aim to improving prescriptions and should allow implement training plans that contribute to therapy more effective and safe.

Keywords : Skin; Bacterial Infections; Anti-Infective Agents; Cellulitis; Pharmacoepidemiology.

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