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CES Medicina

Print version ISSN 0120-8705


OCAMPO-PALACIO, Alejandro et al. Prescription of antibiotics in infections of the skin and soft tissues. CES Med. [online]. 2018, vol.32, n.1, pp.3-13. ISSN 0120-8705.


Infections of skin and soft tissues are common in clinical practice, which may even be responsible for sepsis and severe complications.


To describe the prescription of antimicrobials and variables associated with their use in patients with diagnosis of infections of skin and soft tissues in a primary care hospital.

Materials and Methods:

Cross-sectional study in patients hospitalized for infections of the skin between 1 January and 31 December 2014. A simple random sampling was performed. Were included sociodemographic, clinical and pharmacological variables from medical records. Treatment was defined as adequate when there was a correlation between the diagnosis of each patient according to the International Classification of Diseases (ICD-10) as purulent or non-purulent infection, severity (mild, moderate or severe) and prescribed medication. Multivariate analysis using. SPSS 22.0.


A total of 309 patients were included, and the penicillins corresponded to the initial most formulated antibiotics (81.7 % of cases); 231patients (74.8 %) had well indicated antibiotic treatment. Comorbid conditions most frequently found in patients of this cohort were antiinflammatory drugs (NSAIDs) (61.2 %). Receiving the first oral antibiotic was less likely that the prescription was inadequate (OR:0.215;IC95 %:0.115-0.400).


The data obtained should be aim to improving prescriptions and should allow implement training plans that contribute to therapy more effective and safe.

Keywords : Skin; Bacterial Infections; Anti-Infective Agents; Cellulitis; Pharmacoepidemiology.

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