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CES Medicina

Print version ISSN 0120-8705


QUINTERO-RODRIGUEZ, Katherine et al. Undifferentiated embryonal sarcoma in two pediatric patients. CES Med. [online]. 2018, vol.32, n.3, pp.301-309. ISSN 0120-8705.

Undifferentiated embryonal sarcoma, an infrequent malignant mesenchymal liver tumor, occupies the third place in frequency of primary neoplasms of the liver in infancy. It has a fast-growing rate; the most frequent symptoms are pain and abdominal mass, also jaundice, weight loss, fever, emesis and hepatomegaly. The diagnosis is made taking into account the imaging findings, immune-histochemical studies and pathological analysis, the latter providing the definitive diagnosis. The prognosis of this tumor was initially poor, with survival rates of less than 1 year; however, with the introduction of chemotherapy associated with surgical resection, long-term survival has improved with the possibility of cure, directly related to timely treatment. In this article, two cases of undifferentiated embryonal sarcoma in pediatric patients are presented, diagnosed in the Fundación Cardioinfantil-Instituto de Cardiología, confirmed by pathology. Finally, the histopathological characteristics, imaging findings, differential diagnoses and the therapeutic options used are discussed, as reported in the literature.

Keywords : Sarcoma; Hepatic neoplasms; Tomography; Ultrasound; Adjuvant chemotherapy.

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