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CES Medicina

Print version ISSN 0120-8705

Abstract

GIRALDO-BAHAMON, Germán et al. Evaluation of the bone marrow in cytopenic patients infected with human immunodeficiency virus type 1 in a third level Colombian hospital. CES Med. [online]. 2019, vol.33, n.3, pp.165-174. ISSN 0120-8705.  https://doi.org/10.21615/cesmedicina.33.3.1.

Objective:

To describe the findings in the study of bone marrow of patients with human immunodeficiency virus (HIV) infection who present some type of cytopenia in a highly complex hospital in southern Colombia.

Materials and methods:

Retrospective descriptive study of case series. All adult pa tients with confirmed HIV infection who presented some type of cytopenia during January 2011 to December 2014 at the University Hospital Hernando Moncaleano Perdomo de Neiva, were included. A total of 37 patients com pleted the inclusion criteria.

Results:

the median age was 35 years, 59 % men; in 48.6 % of the individuals, the time of diagnosis by HIV was less than one year and 59 % did not receive antiretroviral therapy at the time of admission. A median was found in a leukocyte count of 2400 cells / mm3, neutrophils of 1400 cells / mm3, CD4 lymphocytes of 43 cells / mm3. The bone marrow study was positive in 27 % of the cases (10 patients), finding disseminated opportunistic infection in six patients; two neoplasms, plus a medullar hypoplasia and a case of megaloblastic anemia.

Conclusion:

The study of bone marrow in patients with HIV infection is a useful tool and should be performed in all patients with HIV infection with advanced disease in the study of cytopenia associated or not with fever.

Keywords : Acquired immunodeficiency syndrome; Human immunodeficiency virus; Bone marrow; Anemia.

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