Abstract

SOSA DELGADO, Nallely; MARTINEZ, Dianny  and  LUGO, Judith. Vaccine and non-vaccine serotypes of Streptococcus pneumoniae in children from Latin America: a review of the last SIREVA II report. CES Med. [online]. 2020, vol.34, n.3, pp.179-187.  Epub July 15, 2021. ISSN 0120-8705.  https://doi.org/10.21615/cesmedicina.34.3.1.

Streptococcus pneumoniae infections are among the leading causes of death from vaccine-preventable diseases in children under the age of 5. There are currently conjugated vaccines against several S. pneumoniae serotypes, thus the introduction of this type of vaccine has been a good strategy for immunizing the population at risk, in addition to indirectly contributing to the decrease in antimicrobial resistance. A review of the last available report of circulating S. pneumoniae serotypes in children under five years of age residing in Latin America was performed. Vaccine serotypes 19A, 3, 14, 1 and non-vaccine serotype 12F were the most frequent. In Latin America the implementation of the PCV13 vaccine continues to be an excellent option; however, with the introduction of conjugate vaccines, the phenomenon of replacement disease has been evidenced by the circulation of diverse non-vaccine serotypes. Epidemiological studies in Latin American countries are necessary to monitor vaccination strategies and the effect of conjugate vaccines in the region.

Keywords : Streptococcus pneumoniae; Serotyping; Vaccines conjugate.

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