Abstract

VALLEJOS-NARVAEZ, Álvaro et al. Metformin-associated lactic acidosis. CES Med. [online]. 2021, vol.35, n.2, pp.185-192.  Epub Feb 11, 2022. ISSN 0120-8705.  https://doi.org/10.21615/cesmedicina.5589.

Lactic acidosis is an adverse reaction related to metformin and is the main etiology of metabolic acidosis. An annual incidence of lactic acidosis of 4.3 cases per 100 000 users of this drug has been reported, which is a considerable amount considering that about 150 million patients diagnosed with type 2 diabetes mellitus use the drug. We report the case of an 81-year-old patient with type 2 diabetes mellitus managed with metformin which, added to the presence of multiple comorbidities, favored the development of lactic acidosis.

Keywords : Lactic acidosis; Metformin; Drug-Related side effects and adverse reactions; Diabetes..

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