Abstract

CORREA-PARRA, Laura; VILLA-SALDARRIAGA, María Paulina  and  FORERO-SALDARRIAGA, Santiago. Dermatitis herpetiformis: specific manifestation of celiac disease. CES Med. [online]. 2021, vol.35, n.3, pp.272-283.  Epub Apr 07, 2022. ISSN 0120-8705.  https://doi.org/10.21615/cesmedicina.6352.

Celiac disease is a systemic disorder with an autoimmune basis, secondary to continuous exposure to gluten in people with genetic susceptibility, which leads to the development of specific antibodies mainly affecting the small intestine with subsequent enteropathy. The clinical manifestations include digestive symptoms and extra intestinal manifestations. In this last group, the dermatological manifestations stand out, specifically dermatitis herpetiformis, which is considered specific to Celiac disease. It presents clinically as a pruritic papulovesicular rash. The diagnosis is based on a skin biopsy with direct immunofluorescence and the presence of anti-tissue transglutaminase 2 antibodies, only in specific cases it should be complemented with other studies. Treatment is based on a gluten-free diet, which improves symptoms, controls and prevents complications of Celiac disease, such as digestive neoplasms and the development of other autoimmune diseases.

Keywords : celiac disease; skin diseases; dermatitis herpetiformis; diet; gluten-free.

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