Abstract

CARVAJAL, Tomas; FRANCO, Diana L; MARTINEZ, Adriana  and  PENA, Iván M. Marburg's variant of multiple sclerosis: report of an atypical case. Acta Neurol Colomb. [online]. 2012, vol.28, n.2, pp.94-100. ISSN 0120-8748.

We present a 58 years old woman with multiple sclerosis diagnosed in 2007, she was treated with interferon and methylprednisolone with a stable disease until last year. Recently she had had multiple episodes of exacerbations. Patient was admitted for a rapidly progressive neurological deterioration. When evaluated the patient had a Glasgow scale of 4/15 (Best eye response: 2, Best verbal response: 1, Best motor response: 1). Case was evaluated in a medical board, and was considered an atypical Marburg variant of multiple sclerosis. She was treated with immunoglobulin and mitoxantrone without clinical improvement. Later she developed a distributive shock leading to death.

Keywords : Multiple Sclerosis.

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