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Acta Neurológica Colombiana
Print version ISSN 0120-8748
Abstract
ATEHORTUA DEL LLANO, Mariana and SUAREZ, Juan Camilo. Clinical characterization and cognitive profile before and after surgery for drug-resistant epilepsy. Acta Neurol Colomb. [online]. 2012, vol.28, n.3, pp.133-142. ISSN 0120-8748.
INTRODUCTION: epilepsy is a common disorder worldwide. 80% is controlled with medication, but 20 to 40% of cases, are drug-resistant epilepsy. 40% of these cases originate in the temporal lobe and 20% in the frontal lobe. The most common cause is temporal lobe epilepsy and surgery is an alternative treatment. OBJETIVE: describe the clinical characteristics and changes in neuropsychological tests before and after surgery drug-resistant epilepsy. MATERIALS AND METHODS: descriptive study in a series of 38 patients with two clinical and neuropsychological assessments (pre and post) to the surgery. RESULTS: 73.7% (28/38) had mesial temporal sclerosis and 13.2% definite signs of mesial temporal sclerosis, both by MRI report. The most common epileptogenic zone was temporary (97.3%), reaching 37.8% on the right side, 32.4% bitemporal and 29.7% on the left side. There is maintenance of cognitive function before and after surgery. CONCLUSION: the drug-resistant epilepsy surgery is in itself a technique of neuro rehabilitation; removing the structural or functional deficit, providing an effective response to remediable epileptic syndromes, in which the preservation of cognitive function must be goal and result.
Keywords : Cognition; Disabled Persons; Epilepsy; Temporal Lobe; Neurosurgery; Rehabilitation.