SciELO - Scientific Electronic Library Online

 
vol.30 issue2Factors associated with quality of life in patients with carpal tunnel syndromeMortality behavior of Parkinson's disease in Chile 1990-2009 author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Acta Neurológica Colombiana

Print version ISSN 0120-8748

Abstract

CORDOBA, Juan Pablo et al. Therapeutic plasma exchange in immune-mediated neurological diseases: four-year experience at the University Hospital San Ignacio, Bogotá, Colombia. Acta Neurol Colomb. [online]. 2014, vol.30, n.2, pp.89-96. ISSN 0120-8748.

Introduction. Plasma exchange (PE) has become a therapeutic treatment for many neurological diseases. Each day more scientific papers are being published with evidence that approves PE for patients with immunological mediated neurological disorders. It is important to register our local experience with PE in order to understand the clinical answer to the therapy in our population. Objective. To describe the experience of the Hospital Universitario San Ignacio in treating patients with neurological disorders with PE, during a 4 year period. Materials and methods. Observational retrospective study, which describes the patients, PE technique, complications of therapy and clinical answer of patients with neurological conditions treated with PE. Results. 106 sessions of PE in 16 patients, corresponding to 23 procedures. The average age was 43 years, 81% of patients were female. 83% of sessions were done for Myasthenia gravis, the rest were done for treatment of Guillain-Barré, Optical Neuromyelitis, multifocal motor neuropathy and autoimmune encephalitis. All sessions were done by membrane filtration technique. The average plasma volume exchange was 1.3, and 20 sessions presented at least one complication. The neurological response of the patients was the expected and was similar to those reported in the literature. Conclusions. Based on the experience of our medical center, PE is a safe and effective therapy for patients with some immunological mediated neurological disorders.

Keywords : Apheresis; Plasma Exchange; Plasmapheresis; Myasthenia Gravis; Neuromielítis Optica.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )