Abstract

CHILATRA FONSECA, José Mauricio  and  VILLAMIZAR SCHILLER, Ives Teófilo. Cerebral sinovenous thrombosis associated with antiphospholipid syndrome in a pediatric patient. Acta Neurol Colomb. [online]. 2015, vol.31, n.1, pp.60-64. ISSN 0120-8748.  https://doi.org/10.22379/242240229.

Cerebral sinovenous thrombosis is a relatively rare disorder in the pediatric population, it has been associated with multiple conditions and risk factors such as local or systemic infections, cardiac malformations, trauma, dehydratation, chronic diseases and especially genetic prothrombotic factors. The location may vary depending on the etiology and may occur with a wide variability in symptoms and signs depending on the age of the patient. Case: 5 year-old male patient, with episodes of self-resolving headache and intermittent ataxia starting at 2 years of age. The patient later presents focal motor seizures, followed by a super refractory status epilepticus. The magnetic resonance imaging (brain MRI and magnetic resonance angiography) shows evidence of a partial cerebral venous deep sinus thrombosis associated with ischemic stroke in globus pallidus, midbrain and cerebellar hemispheres. The patient is positive for IgM anticardiolipin antibody and lupus anticoagulant, where pediatric rheumatology and hematology confirmed diagnosis of cerebral venous sinus thrombosis secondary to antiphospholipid syndrome. Clinical improvement was achieved by implementing immunotherapy plus anticoagulation.

Keywords : Intracranial Sinus Thrombosis; Antiphospholipid síndrome; Child Preschool.

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