Abstract

PALACIOS SANCHEZ, Eduardo et al. Non-Motor Symptoms in Parkinson's disease, Relationship to laterality at the beginning of the disease?. Acta Neurol Colomb. [online]. 2015, vol.31, n.3, pp.261-266. ISSN 0120-8748.

Introduction: Parkinson's disease courses with non-motor symptoms , which may go unnoticed. The reported prevalence is 21 % at diagnosis of the disease, and up to 88% after seven years of evolution. Attempts to approximate the laterality of onset of motor symptoms with non-motor manifestations, severity and prognosis; however, the results are not conclusive, whereby conducted this study. Objective: to describe if the frequency of non motor symptoms is higher acording to laterality at the start of motor symptoms in patients with Parkinson's disease (PD). Materials and methods: cross-sectional study. Included Patients attending neurology between April 2011 and February 2015. NMS Quest questionnaire was used. Results: 156 patients were admitted, the average age was 69.1 years (SD 9.4), 52% male, with an median time of PD evolution of five years; the most common non-motor symptom was feeling sad or low mood. No significant increase in the presence of non-motor symptoms was documented in the analysis Start by laterality. Conclusion: we found no relationship between laterality of onset of motor symptoms and frequency of presentation of non-motor symptoms.

Keywords : Nigrostriatal Degeneration; Functional Laterality; No Motor Manifestations (MeSH).

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