Abstract

ESCOBAR-CORDOBA, Franklin; ALVAREZ-VANEGAS, Carolina  and  TORRES-ESPINOSA, Laura. Pharmacological treatment of neuroleptic-induced akathisia. Acta Neurol Colomb. [online]. 2015, vol.31, n.4, pp.447-453. ISSN 0120-8748.

Acute Akathisia is a movement disorder rather annoying; characterized by subjective feelings and objective signs of restlessness, which often presents as a side effect of neuroleptics, early treatment is necessary to ensure good adherence to treatment with antipsychotics and prevent relapses. To describe the state of the art of available treatments for neuroleptic-induced acute akathisia, taking into account effectiveness and tolerability. An electronic search in Pubmed, Science Alert, Springer link, SciELO, Ovid and Elsevier with specific eligibility criteria, obtaining 87 studies, of which were chosen 51 of them manually, according to their clinical relevance, topicality and level of evidence. In this paper, we describe the results of the search. The benzodiazepines, centrally acting lipophilic beta-blockers and anticholinergics, are the most studied drugs to treat this movement disorder, the first two have shown superiority; however, considerable research is still needed in this regard.

Keywords : Akathisia; drug-induced; antipsychotic agents; adverse effects; movement disorders; chemically induced; psychomotor agitation.

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