Abstract

FERNANDEZ YEPEZ, Luis José; ESCORCIA BARCELO, Ofelia; MONTOYA JARAMILLO, Mario  and  HERRERA RUIZ, Felipe. Cerebellar syndrome for mesalamine: a case report. Acta Neurol Colomb. [online]. 2016, vol.32, n.2, pp.122-126. ISSN 0120-8748.

Cerebellum is Latin for "little brain" is about a tenth of the brain in size and weight, is in the posterior cranial fossa. It connects directly or indirectly to a variety of structures, including brainstem, spinal cord, cortical and subcortical regions. The cerebellum contains almost 80% of all neurons in the brain and consists of different forms of neuronal units, each sharing basic cerebellar microcircuits. The cerebellum is formed by two lateral hemispheres and vermis or a middle portion . The cerebellum has several functions: coordinate movements specialized volunteers to influence muscle activity and control the balance, muscle tone through connections with the vestibular system, the spinal cord and alpha motor neurons. Within the cerebellar cortex somatotopic organization exists a body part. The cerebellum is a key to information processing and participates in numerous motor and non-motor activities, thanks to the anatomical characteristics of its routes, huge analysis capabilities and high connectivity with other brain areas, can be affected by different factors such as abnormalities in embryonic development, toxic, autoimmune, inflammatory, vascular and metabolic, infections, primary and secondary tumors, trauma, iatrogenic, genetic diseases, sporadic, giving rise to signs and symptoms that cause cerebellar syndrome according to compromised anatomical area. In the scientific literature no reported cases of cerebellar syndrome mesalamina (mesalazina), we report the first case.

Keywords : Aminosalicylic acids; cerebellum; cerebellar diseases; cerebellar vermis; mesalamine; syndrome.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )