Abstract

RAMIREZ, Sergio Francisco et al. Melas syndrome: clinical correlation with imaging findings in spectroscopy and tractography, case report. Acta Neurol Colomb. [online]. 2016, vol.32, n.3, pp.227-232. ISSN 0120-8748.

Melas syndrome is a disease characterized by mitochondrial inheritance of mitochondrial encephalopathy, lactic acidosis and events like stroke secondary to a mutation in the gene encoding the electron transport proteins limiting energy production and generating multiorgan dysfunction being affected mainly musculoskeletal system and the nervous system which correlates with the clinical characteristics presented by patients. The diagnosis is based on clinical suspicion, laboratory, and imaging findings and confirmation of the mutation through genetic study. No specific treatment is Is available, but symptomatic treatment is needed and requires multidisciplinary support. We report a patient with a history of Melas who who had bioccipital cerebral ischemic event and correlation with findings in neuroimaging (spectroscopy and tractography).

Keywords : Melas; spectroscopy; tractography.

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